Independent Cellular Processes for Hippocampal Memory Consolidation and Reconsolidation

@article{Lee2004IndependentCP,
  title={Independent Cellular Processes for Hippocampal Memory Consolidation and Reconsolidation},
  author={Jonathan L. C. Lee and Barry J. Everitt and Kerrie L. Thomas},
  journal={Science},
  year={2004},
  volume={304},
  pages={839 - 843}
}
The idea that new memories undergo a time-dependent consolidation process after acquisition has received considerable experimental support. More controversial has been the demonstration that established memories, once recalled, become labile and sensitive to disruption, requiring “reconsolidation” to become permanent. By infusing antisense oligodeoxynucleotides into the hippocampus of rats, we show that consolidation and reconsolidation are doubly dissociable component processes of memory… 
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This preview presents data on the consolidation and reconsolidation of memories for negative and positive events via reactivation (reminding) obtained using different experimental models. Particular
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