Independence of in vitro iron absorption from mucosal transferrin content in rat jejunal and ileal segments

@article{Schmann1986IndependenceOI,
  title={Independence of in vitro iron absorption from mucosal transferrin content in rat jejunal and ileal segments},
  author={Klaus Sch{\"u}mann and Kurt Osterloh and Wolfgang Forth},
  journal={Blut},
  year={1986},
  volume={53},
  pages={391-400}
}
Isolated non blood-perfused intestinal segments from normal and irondeficient rats were used in vitro. A modification of the luminal perfusion method according to Fisher and Parsons allowed the comparison of iron and transferrin quantities in the serosal fluid at 15 min intervals. Iron transfer in jejunal and ileal segments was directly proportional to the luminal iron concentration within a dose range of 1 to 100 μmol/l, did not show saturation characteristics and was linear over time. Jejunal… CONTINUE READING