Indapamide improves flow-induced dilation in hypertensive rats with a high salt intake.

Abstract

OBJECTIVE Spontaneously hypertensive rats (SHR) are sensitive to a high salt intake and we investigated the question of whether flow-induced dilation is affected by this type of diet, as flow responses are especially sensitive to small changes in extracellular sodium concentrations. METHODS We evaluated the effects of a diuretic (indapamide, 1.5 mg/kg per… (More)

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