Incubation of spermatozoa from asthenozoospermic semen samples with pentoxifylline and 2-deoxyadenosine: variability in hyperactivation and acrosome reaction rates.

Abstract

We examined hyperactivation and acrosomal loss in asthenozoospermic patients with a history of failed in-vitro fertilization (IVF). After selection by a Percoll gradient, spermatozoa were incubated with 3.6 mM pentoxifylline (PTX), 3.0 mM 2-deoxyadenosine (2-DXA) or both. Hyperactivation and ionophore A-23187-induced acrosome reaction were assessed… (More)

Topics

Cite this paper

@article{Tournaye1994IncubationOS, title={Incubation of spermatozoa from asthenozoospermic semen samples with pentoxifylline and 2-deoxyadenosine: variability in hyperactivation and acrosome reaction rates.}, author={Herman J Tournaye and P Wieme and Roel C. Janssens and Geert R Verheyen and Paul Devroey and Andr{\'e} C. van Steirteghem}, journal={Human reproduction}, year={1994}, volume={9 11}, pages={2038-43} }