Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data

@article{Linton2020IncubationPA,
  title={Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data},
  author={Natalie M. Linton and Tetsuro Kobayashi and Yichi Yang and Katsuma Hayashi and Andrei R. Akhmetzhanov and Sung-mok Jung and Baoyin Yuan and Ryo Kinoshita and Hiroshi Nishiura},
  journal={Journal of Clinical Medicine},
  year={2020},
  volume={9}
}
The geographic spread of 2019 novel coronavirus (COVID-19) infections from the epicenter of Wuhan, China, has provided an opportunity to study the natural history of the recently emerged virus. Using publicly available event-date data from the ongoing epidemic, the present study investigated the incubation period and other time intervals that govern the epidemiological dynamics of COVID-19 infections. Our results show that the incubation period falls within the range of 2-14 days with 95… 
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1,134 Citations

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References

SHOWING 1-10 OF 34 REFERENCES
Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases
TLDR
It is argued that the current COVID-19 epidemic has a substantial potential for causing a pandemic and the proposed approach provides insights in early risk assessment using publicly available data.
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
TLDR
There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020
TLDR
Using the travel history and symptom onset of 88 confirmed cases that were detected outside Wuhan in the early outbreak phase, the mean incubation period is estimated to be 6.4 days, which should help inform 2019-nCoV case definitions and appropriate quarantine durations.
The incubation period of 2019-nCoV infections among travellers from Wuhan, China
TLDR
Using the travel history and symptom onset of 88 confirmed cases that were detected outside Wuhan, the mean incubation period of a novel coronavirus 2019-nCoV is estimated to be 6.4 days, ranging from 2.1 to 11.1 days, to inform case definitions for 2019- nCoV and appropriate durations for quarantine.
Real time estimation of the risk of death from novel coronavirus (2019-nCoV) infection: Inference using exported cases
TLDR
It is noted that current 2019-nCoV epidemic has a substation potential to cause a pandemic and the proposed approach can provide insights into early risk assessment using only publicly available data.
Estimates of short- and long-term incubation periods of Plasmodium vivax malaria in the Republic of Korea.
Estimating incubation period distributions with coarse data
TLDR
A sensitivity analysis of the two methods to violations of model assumption is conducted and these methods are applied to historical incubation period data on influenza A and respiratory syncytial virus.
Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings
TLDR
Transmissibility is substantially higher than that of seasonal flu, and comparable with lower estimates of R0 obtained from previous influenza pandemics, by analyzing the outbreak in Mexico, early data on international spread, and viral genetic diversity, which makes an early assessment of transmissibility and severity.
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
The Extent of Transmission of Novel Coronavirus in Wuhan, China, 2020
TLDR
The most plausible number of infections is in the order of thousands, rather than hundreds, and there is a strong indication that untraced exposures other than the one in the epidemiologically linked seafood market in Wuhan have occurred.
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