Incretin-related drug therapy in heart failure.

  title={Incretin-related drug therapy in heart failure.},
  author={Amanda Ruth Vest},
  journal={Current heart failure reports},
  volume={12 1},
The new pharmacological classes of GLP-1 agonists and DPP-4 inhibitors are now widely used in diabetes and have been postulated as beneficial in heart failure. These proposed benefits arise from the inter-related pathophysiologies of diabetes and heart failure (diabetes increases the risk of heart failure, and heart failure can induce insulin resistance) and also in light of the dysfunctional myocardial energetics seen in heart failure. The normal heart utilizes predominantly fatty acids for… CONTINUE READING