Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells

  title={Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells},
  author={Yudi Purnomo and D. Soeatmadji and S. Paul Sumitro and M. A. Widodo},
  booktitle={Journal of traditional and complementary medicine},
This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test group (n = 5). Diabetic rats were induced with High Fructose Diet (HFD) and single dose intraperitoneal streptozotocin 25 mg/kg bw. Aqueous leaves extract of U. lobata was prepared by decoction methods and administrated orally with doses of 250, 500, and 1000 mg/kg bw for 4 weeks… CONTINUE READING


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