Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.

@article{Matsuzaki2009IncrementalEO,
  title={Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.},
  author={Masunori Matsuzaki and Mitsuhiro Yokoyama and Yasushi Saito and Hideki Origasa and Yuichi Ishikawa and Shinichi Oikawa and Jun Sasaki and Hitoshi Hishida and Hiroshige Itakura and Toru Kita and Akira Kitabatake and N. Nakaya and Toshiie Sakata and Kazuyuki Shimada and Kunio Shirato and Yuji Matsuzawa},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2009},
  volume={73 7},
  pages={1283-90}
}
BACKGROUND Results from JELIS (Japan EPA Lipid Intervention Study) demonstrated the efficacy of pure eicosapentaenoic acid (EPA) in preventing coronary artery disease (CAD) in hypercholesterolemic patients under statin treatment. The present study examined in detail whether EPA is effective for the secondary prevention of CAD. METHODS AND RESULTS Patients with established CAD and a total cholesterol level > or =250 mg/dl were observed with a mean follow-up of 4.6 years. They were randomly… CONTINUE READING
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