Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease.

BACKGROUND Recent clinical trials found that high-dose statin therapy, compared with conventional-dose statin therapy, reduces the risk of cardiovascular events in patients with acute coronary syndromes (ACS) and stable coronary artery disease (CAD). However, the actual benefit and cost-effectiveness of high-dose statin therapy are unknown. METHODS AND… CONTINUE READING