Increasing the specific expression of Cdk9 gene by single-stranded adult microRNA-1 in fibroblast cells

@inproceedings{Bolandi2017IncreasingTS,
  title={Increasing the specific expression of Cdk9 gene by single-stranded adult microRNA-1 in fibroblast cells},
  author={Zohre Bolandi and Hosein Ghanbarian},
  year={2017}
}
Backgrond: MicroRNAs (miRNAs) are endogenous, non-coding short RNAs (~22 nucleotides) that can downregulate gene expression by repression of translation, mRNA degradation, or transcriptional repression. miRNA misregulation has been implicated in pathogenic alterations such as cancer. In order to investigate the microRNA functions in gene regulation and/or to modulate their expression in pathogenic conditions, microRNAs are overexpressed by using plasmid or synthetic RNA duplexes designed to… CONTINUE READING

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