Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.

@article{HabrGama2009IncreasingTR,
  title={Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: results of a prospective study using additional chemotherapy during the resting period.},
  author={Angelita Habr-Gama and R O Perez and Jorge Sabbaga and Wladimir Nadalin and Guilherme Pagin S{\~a}o Juli{\~a}o and Joaquim Jos{\'e} Gama-Rodrigues},
  journal={Diseases of the colon and rectum},
  year={2009},
  volume={52 12},
  pages={1927-34}
}
OBJECTIVES Addition of chemotherapy in the resting period between radiotherapy completion and response assessment during neoadjuvant treatment for distal rectal cancer could potentially increase rates of complete tumor regression. The purpose of this study was to evaluate toxicity rates and the impact of an extended neoadjuvant chemoradiation regimen on complete response rates. METHODS Thirty-four consecutive patients with nonmetastatic distal rectal cancer were prospectively included… CONTINUE READING

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An interval 7 weeks between neoadjuvant therapy and surgery DISEASES OF THE COLON & RECTUM

  • H Tulchinsky, E Shmueli, A Figer, JM Klausner, M. Rabau
  • VOLUME 52:
  • 2009
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