Increasing the forensic discrimination of mitochondrial DNA testing through analysis of the entire mitochondrial DNA genome.

@article{Parsons2001IncreasingTF,
  title={Increasing the forensic discrimination of mitochondrial DNA testing through analysis of the entire mitochondrial DNA genome.},
  author={T. J. Parsons and Michael D. Coble},
  journal={Croatian medical journal},
  year={2001},
  volume={42 3},
  pages={304-9}
}
The principal limitation in forensic mitochondrial DNA (mtDNA) testing is the low power of discrimination that is obtained when common "mtDNA types" are involved in a case. Currently, an "mtDNA type" refers to the sequence within hypervariable regions I and II (HV1/HV2) of the control region, approximately 610 bp. In Caucasians, the most common HV1/HV2 type is found in approximately 7% of the population and there are 12 additional types found at greater than approximately 0.5% (ignoring HV2 C… CONTINUE READING

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