Increasing the efficiency of searches for the maximum likelihood tree in a phylogenetic analysis of up to 150 nucleotide sequences.

@article{Morrison2007IncreasingTE,
  title={Increasing the efficiency of searches for the maximum likelihood tree in a phylogenetic analysis of up to 150 nucleotide sequences.},
  author={David A. Morrison},
  journal={Systematic biology},
  year={2007},
  volume={56 6},
  pages={988-1010}
}
Even when the maximum likelihood (ML) tree is a better estimate of the true phylogenetic tree than those produced by other methods, the result of a poor ML search may be no better than that of a more thorough search under some faster criterion. The ability to find the globally optimal ML tree is therefore important. Here, I compare a range of heuristic search strategies (and their associated computer programs) in terms of their success at locating the ML tree for 20 empirical data sets with 14… CONTINUE READING

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