Increasing the Number of SNP loci does not Necessarily Improve Prediction Power at Least in the Comparison of MTHFR SNP and Haplotypes

Abstract

BACKGROUND Rapid advances in genotyping technology have made it possible to easily utilize a large number of genetic markers. According to information theory, an increase in the number of markers provides more information; however, the clinical usefulness does not increase linearly. This study aimed to assess the effect of folic acid supplementation… (More)

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