Increasing role of cytogenetics in pediatric practice.

@article{Dayakar2010IncreasingRO,
  title={Increasing role of cytogenetics in pediatric practice.},
  author={Seetha Dayakar and Didala Swaroopa Rani and Sidam Jangu Babu and Komanduri Srilatha and Undamatla Jayanthi and Kalal Iravathy Goud and Dharmendra Jain and Vimarsh Raina},
  journal={Genetic testing and molecular biomarkers},
  year={2010},
  volume={14 2},
  pages={197-204}
}
Karyotyping was done in 100 children suspected of having chromosomal abnormalities of genetically uncertain syndromes, multiple congenital anomalies, short stature, dysmorphic features, unclassified mental retardation, and Down syndrome. A total of 56 patients had an abnormal karyotype: ring chromosome of 13 was seen in 1 patient (1.78%), and trisomy 21 was seen in 29 patients (51.78%) who were diagnosed as Down syndrome patients. Among them, 9 were male patients (31.03%) (47,XY+21) and 18 were… CONTINUE READING