Increasing organ blood flow during cardiopulmonary bypass in pigs: comparison of dopamine and perfusion pressure.

@article{Mackay1995IncreasingOB,
  title={Increasing organ blood flow during cardiopulmonary bypass in pigs: comparison of dopamine and perfusion pressure.},
  author={Julian Mackay and A E Feerick and Lee Woodson and Cheng Yung Lin and Donald J. Deyo and Taisuke Uchida and William E. Johnston},
  journal={Critical care medicine},
  year={1995},
  volume={23 6},
  pages={1090-8}
}
OBJECTIVE To determine whether low-dose dopamine infusion (5 micrograms/kg/min) during cardiopulmonary bypass selectively increases perfusion to the kidney, splanchnic organs, and brain at low (45 mm Hg) as well as high (90 mm Hg) perfusion pressures. DESIGN Randomized crossover trial. SETTING Animal research laboratory in a university medical center. SUBJECTS Ten female Yorkshire pigs (weight 29.9 +/- 1.2 kg). INTERVENTION Anesthetized pigs were placed on normothermic cardiopulmonary… CONTINUE READING

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