Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Abstract

Parkinson's disease (PD) is a common chronic neurodegenerative disorder, usually of idiopathic origin. Symptoms including tremor, bradykinesia, rigidity and postural instability are caused by the progressive loss of dopaminergic neurons in the nigrostriatal region of the brain. Symptomatic therapies are available but no treatment slows or prevents the loss… (More)
DOI: 10.1016/j.expneurol.2015.07.024

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@article{Mounsey2015IncreasingLO, title={Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease}, author={Ross B. Mounsey and Sarah Mustafa and Lianne Robinson and Ruth A. Ross and Gernot Riedel and Roger G Pertwee and Peter Teismann}, journal={Experimental Neurology}, year={2015}, volume={273}, pages={36-44} }