Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events.

@article{Biasucci1999IncreasingLO,
  title={Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events.},
  author={Luigi Marzio Biasucci and Giovanna Liuzzo and Giamila Fantuzzi and Giuseppina Caligiuri and Antonio Giuseppe Rebuzzi and Francesca Ginnetti and Charles A Dinarello and Attilio Maseri},
  journal={Circulation},
  year={1999},
  volume={99 16},
  pages={
          2079-84
        }
}
BACKGROUND A growing body of evidence suggests a role for inflammation in acute coronary syndromes. The aim of this study was to assess the role of proinflammatory cytokines, their time course, and their association with prognosis in unstable angina. METHODS AND RESULTS We studied 43 patients aged 62+/-8 years admitted to our coronary care unit for Braunwald class IIIB unstable angina. In each patient, serum levels of interleukin-1 receptor antagonist (IL-1Ra), interleukin-6 (IL-6) (which… CONTINUE READING
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Randomised trial of roxithromycin in non-Q wave coronary syndromes: ROXIS pilot study.Lancet

  • E Gurfinkel, G Bozovich, A Deroca, E Beck, B. Mautner
  • 1997