Increasing complexity of the dystrophin-associated protein complex.

  title={Increasing complexity of the dystrophin-associated protein complex.},
  author={Jonathon M. Tinsley and Derek J Blake and Richard A. Zuellig and K. E. Davies},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={91 18},
Duchenne muscular dystrophy is a severe X chromosome-linked, muscle-wasting disease caused by lack of the protein dystrophin. The exact function of dystrophin remains to be determined. However, analysis of its interaction with a large oligomeric protein complex at the sarcolemma and the identification of a structurally related protein, utrophin, is leading to the characterization of candidate genes for other neuromuscular disorders. 
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Neuromuscular Disorders

  • M. Lambert, P. Chafey, +7 authors H. Gilgenkrantz
  • 1993

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