Increasing Levels of Leukocyte-Derived Inflammatory Mediators in Plasma and cAMP in Platelets during Follow-Up after Acute Cerebral Ischemia

@article{Anwaar1998IncreasingLO,
  title={Increasing Levels of Leukocyte-Derived Inflammatory Mediators in Plasma and cAMP in Platelets during Follow-Up after Acute Cerebral Ischemia},
  author={I. Anwaar and A. Gotts{\"a}ter and K. Ohlsson and I. Mattiasson and F. Lindg{\"a}rde},
  journal={Cerebrovascular Diseases},
  year={1998},
  volume={8},
  pages={310 - 317}
}
Inflammatory mediators secreted by activated leukocytes play a role in the pathogenesis of atherosclerosis. They may also affect the production of vasodilatory and platelet antiaggregatory factors such as nitric oxide (NO) and prostacyclin (PGI2) from the vascular endothelium. Production of NO and PGI2, the effecs of which are mediated by cyclic 3′,5′-guanosine monophosphate (cGMP) and cyclic 3′,5′-adenosine monophosphate (cAMP), respectively, is disturbed in atherosclerosis, whereas increased… Expand
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