Increasing Kaposi's sarcoma‐associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985

@article{Olsen1998IncreasingKS,
  title={Increasing Kaposi's sarcoma‐associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985},
  author={Sonja J Olsen and Yuan Chang and Patrick S. Moore and Robert J. Biggar and Mads Melbye},
  journal={AIDS},
  year={1998},
  volume={12},
  pages={1921–1925}
}
Background:Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a newly discovered virus found in all forms of KS. In the United States, KSHV infection appears to be most common amongst individuals at high-risk for KS. Preliminary data from Africa suggest that KSHV infection may be much more common in the general population. Objective:To examine the KSHV seroprevalence and age-specific patterns of infection in an African country with high rates of KS. Design:Cross-sectional seroprevalence… 
The epidemiology of Kaposi’s sarcoma associated-herpesvirus in Uganda
TLDR
An investigation of factors that might impact on transmission of Kaposi’s sarcoma associated-herpesvirus (KSHV) and the first prospective study of antibody titre to KSHV to determine risk of KS from Africa are described and reported.
Review of the distribution of Kaposi's sarcoma-associated herpesvirus (KSHV) in Africa in relation to the incidence of Kaposi's sarcoma
TLDR
The evidence reviewed here shows that the causal virus–Kaposi's sarcoma associated herpesvirus (KSHV)–is prevalent in many African countries, including places where Kaposi's Sarcoma was almost unknown before HIV, and that it is as common in women as in men.
Kaposi’s Sarcoma-Associated Herpesvirus: Epidemiology, Biological Characteristics and Pathogenesis
TLDR
Globally useful or population-based prognostic and predictive biomarkers for KSHV-related disorders still need to be defined to guide physicians in the choice of therapeutic strategies and to selectively monitor patients at risk.
OPTIMIZATION OF A SEROLOGICAL ASSAY SYSTEM FOR ESTABLISHING INFECTION OF KAPOSI'S SARCOMA ASSOCIATED HERPESVIRUS (KSHV) IN MULTIPLE POPULATIONS AT VARYING LEVELS OF RISK
TLDR
A systematic approach was used to standardize the assessment of KSHV infection rates and examined seroprevalence rates among high-risk populations of clinical interest and identified two multi-antigen algorithms: one that maximized sensitivity and one that Maximized specificity.
Humoral and cellular immune responses against Kaposi's sarcoma-associated herpesvirus (KSHV).
TLDR
Seroepidemiological studies were conducted in African, Middle Eastern, Mediterranean European and South American countries to determine the infection rate, and to determine risk factors and possible routes of KSHV transmission, and a new quantitative real-time PCR method was developed to detect K SHV in clinical samples.
Seroepidemiology and molecular epidemiology of Kaposi's sarcoma-associated herpesvirus among Jewish population groups in Israel.
TLDR
The presence of K SHV in Jews in Israel of all ethnic origins and their high incidence of reported Kaposi's sarcoma suggest that KSHV was introduced into the Jewish population prior to the major Diaspora.
Prevalence of Kaposi's sarcoma‐associated herpesvirus infection in haemophilic patients
TLDR
The seroprevalence of KSHV in patients with haemophilia was investigated by serological methods (anti-KSHV antibodies) and detection of K SHV DNA in blood by using the BCP-1 cell line.
Prevalence of human herpesvirus 8 infection before the acquired immunodeficiency disease syndrome-related epidemic of Kaposi's sarcoma in East Africa.
TLDR
Assessment of the KSHV/HHV8 seroprevalence in the rural populations of the West Nile District in Uganda and the North Mara District in Tanzania during the period prior to the onset of the AIDSrelated epidemic of KS indicates that, during the 1970s, inhabitants of rural areas of Uganda and Tanzania exhibited an overall KSHv/ HHV8Serop revalence similar to that observed in recent years.
Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus.
  • C. Boshoff, R. Weiss
  • Medicine
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2001
TLDR
The histogenesis, clonality and pathology of the tumours are described, together with the epidemiology and possible modes of transmission of the virus.
...
...

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