Increasing Coverage and Efficiency of Measles, Mumps, and Rubella Vaccine and Introducing Universal Varicella Vaccination in Europe: A Role for the Combined Vaccine

@article{Vesikari2007IncreasingCA,
  title={Increasing Coverage and Efficiency of Measles, Mumps, and Rubella Vaccine and Introducing Universal Varicella Vaccination in Europe: A Role for the Combined Vaccine},
  author={Timo Vesikari and Catherine Sadzot-Delvaux and Bernard Rentier and Anne Gershon},
  journal={The Pediatric Infectious Disease Journal},
  year={2007},
  volume={26},
  pages={632-638}
}
Universal mass vaccination according to a 2-dose measles-mumps-rubella (MMR) vaccine schedule is recommended by the World Health Organization and is fundamental to the control of these important diseases. Very high coverage (first dose, ≥95%; second dose, ≥80%) is necessary to achieve and sustain high population immunity, and eventually interrupt indigenous transmission of these diseases. In 2006, the Advisory Committee on Immunization Practices issued a recommendation for 2 doses of varicella… 
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49 Citations
Highly Influential Citations
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Background Citations
16
Methods Citations
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49 Citations

Citation Type

Citation Type

Safety and immunogenicity of a measles-mumps-rubella-varicella vaccine given as a second dose in children up to six years of age.
Live Attenuated Measles Mumps and Rubella Vaccines: An Over View
TLDR
The use of MMR or the recently developed MMR-V (Varicella) vaccine combination benefited from the established clinical surveillance, efficient-technology transfer and proper manufacturing, in addition to the cost effectiveness of these vaccines.
Vaccines for measles, mumps, rubella, and varicella in children.
TLDR
The effectiveness, safety, and long- and short-term adverse effects associated with the trivalent MMR vaccine, containing measles, rubella, mumps, and varicella strains (MMR), or tetravalent vaccine, given to children aged up to 15 years are assessed.
Vaccines for measles, mumps, rubella, and varicella in children.
TLDR
The effectiveness, safety, and long- and short-term adverse effects associated with the trivalent MMR vaccine, containing measles, rubella, mumps, and varicella strains (MMR), or tetravalent vaccine, given to children aged up to 15 years are assessed.
Measles–Mumps–Rubella–Varicella Combination Vaccine (ProQuad®): A Guide to Its Use in Children in the EU
  • L. Scott
  • Medicine, Biology
    Pediatric Drugs
  • 2015
TLDR
Clinical data in young children indicates that vaccination with ProQuad® is as immunogenic as the component vaccines, provides long-term protection against these potentially serious childhood infections and has an acceptable safety profile.
Immunogenicity and safety of measles-mumps-rubella-varicella (MMRV) vaccine followed by one dose of varicella vaccine in children aged 15 months-2 years or 2-6 years primed with measles-mumps-rubella (MMR) vaccine.
Immunogenicity and safety of combined measles-mumps-rubella-varicella vaccine using new measles and rubella working seeds in healthy children in Taiwan and Singapore
TLDR
Both vaccines exhibited an acceptable safety profile in Taiwanese and Singaporean children and non-inferiority of MMRV new WS to MMRV in terms of post-dose-1 seroconversion rates was achieved for all vaccine antigens.
Immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine: an open-labeled, randomized trial in healthy Korean children
TLDR
Based on the pre-specified non-inferiority criterion, SCRs of the MMRV vaccine were non- inferior to that elicited by MMR+V vaccines for all antigens except mumps.
New combination vaccines: integration into pediatric practice.
TLDR
Data suggest that the use of combination vaccines has positive effects on both rates and timeliness of immunizations, and there are also difficult-toquantify costs that may be greater with combined vaccines.
Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella.
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References

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