Increases of Calbindin-Containing Chandelier Cartridges in Schizophrenia: Fact or Artifact?

  title={Increases of Calbindin-Containing Chandelier Cartridges in Schizophrenia: Fact or Artifact?},
  author={F. Benes},
  journal={Biological Psychiatry},
  • F. Benes
  • Published 2017
  • Chemistry, Medicine
  • Biological Psychiatry
In a recent article on the prefrontal cortex (PFC), Rocco et al. (1) reported that immunoreactivity (IR) associated with the vesicular gamma-aminobutyric acid (GABA) transporter (vGAT), glutamic acid decarboxylase 67 (GAD67) protein, and calbindin (CB) showed a 2.7-fold increase in chandelier cell (ChC) cartridges positive for both vGAT and CB (vGAT1/CB1) in layers 2 and 3a in the PFC of schizophrenia (SZ) subjects. This finding was unexpected because an earlier study by Pierri et al. (2… Expand


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Amygdalocortical Circuitry in Schizophrenia: From Circuits to Molecules
  • F. Benes
  • Psychology
  • Neuropsychopharmacology
  • 2010
Alterations in a Unique Class of Cortical Chandelier Cell Axon Cartridges in Schizophrenia