Increases in oxidative stress in the progeny of X-irradiated cells.

  title={Increases in oxidative stress in the progeny of X-irradiated cells.},
  author={Rebecca E Rugo and Robert H. Schiestl},
  journal={Radiation research},
  volume={162 4},
A number of phenotypes persist in the progeny of irradiated cells for many generations including delayed reproductive death, cell transformation, genomic instability, and mutations. It appears likely that persistent phenotypes are inherited by an epigenetic mechanism, although very little is known about the nature of such a mechanism or how it is established. One hypothesis is that radiation causes a heritable increase in oxy-radical activity. In the present study, intracellular levels of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 24 extracted citations

A mitohormetic response to pro-oxidant exposure in the house mouse.

American journal of physiology. Regulatory, integrative and comparative physiology • 2018
View 1 Excerpt

From radioresistance to radiosensitivity: In vitro evolution of L5178Y lymphoma.

International journal of radiation biology • 2015
View 1 Excerpt

Similar Papers

Loading similar papers…