Increases in oxidative stress in the progeny of X-irradiated cells.

@article{Rugo2004IncreasesIO,
  title={Increases in oxidative stress in the progeny of X-irradiated cells.},
  author={Rebecca E Rugo and Robert H. Schiestl},
  journal={Radiation research},
  year={2004},
  volume={162 4},
  pages={416-25}
}
A number of phenotypes persist in the progeny of irradiated cells for many generations including delayed reproductive death, cell transformation, genomic instability, and mutations. It appears likely that persistent phenotypes are inherited by an epigenetic mechanism, although very little is known about the nature of such a mechanism or how it is established. One hypothesis is that radiation causes a heritable increase in oxy-radical activity. In the present study, intracellular levels of… CONTINUE READING

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