Increases in lung tissue expression of intercellular adhesion molecule-1 are associated with hyperoxic lung injury and inflammation in mice.

@article{Welty1993IncreasesIL,
  title={Increases in lung tissue expression of intercellular adhesion molecule-1 are associated with hyperoxic lung injury and inflammation in mice.},
  author={Stephen E. Welty and Jose L. Rivera and Jonathan F Elliston and Charles V Smith and T Zeb and Christie M. Ballantyne and Charles A. Montgomery and Thomas N Hansen},
  journal={American journal of respiratory cell and molecular biology},
  year={1993},
  volume={9 4},
  pages={393-400}
}
Lung injury caused by breathing enriched oxygen continues to be a major problem in clinical medicine. Experimentally, hyperoxic lung injury is characterized by pulmonary edema and associated neutrophil accumulation. Although extensively investigated, the mechanisms for neutrophil accumulation and the role of this accumulation in hyperoxic lung injury remain controversial. Intercellular adhesion molecule-1 (ICAM-1) is an adhesion molecule that when increased on endothelium by inflammatory… CONTINUE READING