Increases in cytokine and antimicrobial peptide gene expression in horses by immunomodulation with Propionibacterium acnes.

@article{Davis2003IncreasesIC,
  title={Increases in cytokine and antimicrobial peptide gene expression in horses by immunomodulation with Propionibacterium acnes.},
  author={Elizabeth G. Davis and Bonnie R. Rush and Frank Blecha},
  journal={Veterinary therapeutics : research in applied veterinary medicine},
  year={2003},
  volume={4 1},
  pages={5-11}
}
Immunomodulation with Propionibacterium acnes is used for prophylaxis of respiratory disease or in horses suffering from chronic pulmonary inflammation; however, the mechanism for this response is poorly understood. Semiquantitative reverse transcriptase-polymerase chain reaction assays were used to evaluate gene expression of interleukin (IL)-2, IL-10, interferon (IFN)-gamma, and NK-lysin in healthy horses treated with P. acnes. Findings in the study indicated that horses treated with a P… CONTINUE READING

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