Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.

@article{Welman2006IncreasesIC,
  title={Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.},
  author={Arkadiusz Welman and Christopher J Cawthorne and Lourdes Ponce-Perez and Jane Barraclough and Sarah Danson and Stephen Murray and Jeff Cummings and Terry D. Allen and Caroline Dive},
  journal={Neoplasia},
  year={2006},
  volume={8 11},
  pages={
          905-16
        }
}
The levels and activity of c-Src in colorectal cancer cells increase steadily during the course of colorectal carcinogenesis and are most highly elevated in advanced metastatic disease. However, the effects of increases in c-Src activity on the proliferation of colorectal cancer cells during early and late stages of tumorigenesis remain elusive. To study the consequences of increases in c-Src levels and activity on the growth of colorectal cancer cells in later stages of colorectal… CONTINUE READING
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