Increased weight gain after ovariectomy is not a consequence of leptin resistance.

@article{Chen2001IncreasedWG,
  title={Increased weight gain after ovariectomy is not a consequence of leptin resistance.},
  author={Yun-fei Chen and Mark L. Heiman},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2001},
  volume={280 2},
  pages={E315-22}
}
The positive correlation between leptin and body fat mass has caused some investigators to speculate that leptin resistance contributes to obesity. Loss of ovarian function in human and rat is associated with increased fat mass gain and increased circulating leptin levels. To study whether ovariectomy produces leptin resistance, Sprague-Dawley female rats were ovariectomized or sham operated and injected with leptin for 35 days. Ovariectomy (OVX) produced hyperphagia and increased gain in both… CONTINUE READING
29 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Effects of intravenously infused leptin on insulin sensitivity and on the expression of uncoupling proteins in brown adipose tissue

  • I Cusin, J Rouru, KE Zakrzewska, B Jeanrenaud, F. Rohner-Jeanrenaud
  • Endocrinology
  • 1999
1 Excerpt

Similar Papers

Loading similar papers…