Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior.

  title={Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior.},
  author={Niels Eijkelkamp and Annemieke Kavelaars and Sigrid Elsenbruch and Manfred Schedlowski and Gerald J. Holtmann and Cobi J. Heijnen},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={293 4},
During acute and chronic inflammation visceral pain perception is altered. Conflicting data exist, however, on visceral pain perception in the postinflammatory phase. The aim of the present study was to investigate whether visceral pain perception is altered after resolution of dextran sodium sulfate (DSS)-induced inflammation of the colon. Visceral sensory function in mice was assessed by monitoring behavioral responses to intracolonic capsaicin instillation. Two hours later the number of c… 

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