Increased urinary excretion of 16α-hydroxy-pregnenolone in newborn infants with 21-hydroxylase deficiency.

@article{Homoki1979IncreasedUE,
  title={Increased urinary excretion of 16$\alpha$-hydroxy-pregnenolone in newborn infants with 21-hydroxylase deficiency.},
  author={Janos Homoki and Walter Magnes Teller},
  journal={Pediatric Research},
  year={1979},
  volume={13},
  pages={1193-1193}
}
Urinary excretion of total 16α-hydroxypregnenolone (16α-OH-P'O), pregnanetriol (PT) and 11-oxopregnanetriol (11-0-PT) were determined by capillary gas chromatography in 18 healthy neonates and 3 newborn infants with congenital adrenal hyperplasia (CAH) during the first three weeks after birth. In the 4th week of life all CAH-infants demonstrated salt loosing crisis.Conclusion: The determination of urinary excretion of 16α-OH-P'O is a valuable tool in the reliable detection of 21-hydroxylase…