Increased urinary excretion of 8-hydroxydeoxyguanosine in engine room personnel exposed to polycyclic aromatic hydrocarbons.

Abstract

BACKGROUND Previous investigations indicate that engine room personnel on ships are exposed to polycyclic aromatic hydrocarbons (PAH) from oil and oil products, with dermal uptake as the major route of exposure. Several PAH are known carcinogens and mutagens. AIMS To investigate the urinary excretion of a marker for oxidative DNA damage, 8-hydroxydeoxy… (More)

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