Increased urinary excretion of angiotensinogen is associated with risk of chronic kidney disease.

Abstract

BACKGROUND The effect of intrarenal renin-angiotensin system (RAS) activity on risk of chronic kidney disease (CKD) has not been well studied in human subjects. METHODS We investigated the association between urinary angiotensinogen, a reliable biomarker of intrarenal RAS activity, and risk of CKD in 201 patients and 201 controls. CKD was defined as… (More)
DOI: 10.1093/ndt/gfs011

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