Increased urinary 8-hydroxy-2'-deoxyguanosine excretion after ileal neobladder replacement.


OBJECTIVES To examine whether orthotopic neobladder replacement using either ileum or colon segments results in increased oxidative stress, by measuring urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), one of the most commonly used markers for evaluating oxidative DNA damage. PATIENTS, SUBJECTS AND METHODS Urinary levels of 8-OHdG and creatinine, urine… (More)


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