Increased uptake and phosphorylation of 2-deoxyglucose by skeletal muscles in endotoxin-treated rats.

@article{Mszros1987IncreasedUA,
  title={Increased uptake and phosphorylation of 2-deoxyglucose by skeletal muscles in endotoxin-treated rats.},
  author={Karola M{\'e}sz{\'a}ros and Gregory J. Bagby and Charles H Lang and John J. Spitzer},
  journal={The American journal of physiology},
  year={1987},
  volume={253 1 Pt 1},
  pages={
          E33-9
        }
}
Glucose metabolism of respiratory and nonrespiratory muscles of different fiber composition was investigated in conscious rats. The accumulation of phosphorylated 2-deoxyglucose (2DGP) was increased in skeletal muscles by 56-102% and in diaphragm by 236% at 3 h after treatment with 100 micrograms/100 g endotoxin. The increase was still marked at 24 h, whereas it diminished at 48 h in the diaphragm, abdominal muscle, and white portion of the quadriceps. In the red portion of this muscle 2DGP… CONTINUE READING

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