Increased type 3 deiodinase expression in papillary thyroid carcinoma.

  title={Increased type 3 deiodinase expression in papillary thyroid carcinoma.},
  author={M{\'i}rian Romitti and Simone Magagnin Wajner and Nadja Zennig and Iuri Martin Goemann and Ana Laura Bueno and Erika Laurini de Souza Meyer and Ana Luiza Silva Maia},
  journal={Thyroid : official journal of the American Thyroid Association},
  volume={22 9},
BACKGROUND Thyroid hormone regulates a wide range of cellular activities, including the balance between cell proliferation and differentiation. The thyroid-hormone-inactivating type 3 deiodinase (DIO3, D3) has been shown to be reactivated in human neoplasias. Here, we evaluated DIO3 expression in human papillary thyroid carcinoma (PTC). METHODS Tumor and surrounding normal thyroid tissue were collected from 26 unselected patients with PTC. Clinical data were retrospectively reviewed in… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 45 references

pression of transforming growth factor - beta 1 and transforming growth factor - beta Type - II receptor mRNA in papillary thyroid carcinoma

  • JA Knauf, MA Sartor, +7 authors JA Fagin
  • Horm Metab Res
  • 2011

Similar Papers

Loading similar papers…