Increased turnover of FoxP3high regulatory T cells is associated with hyperactivation and disease progression of chronic HIV-1 infection.

@article{Xing2010IncreasedTO,
  title={Increased turnover of FoxP3high regulatory T cells is associated with hyperactivation and disease progression of chronic HIV-1 infection.},
  author={Shaojun Xing and Junliang Fu and Zheng Zhang and Yingying Gao and Yanmei Jiao and Fubiao Kang and Jiyuan Zhang and Chunbao Zhou and Hao Wu and Fu-sheng Wang},
  journal={Journal of acquired immune deficiency syndromes},
  year={2010},
  volume={54 5},
  pages={
          455-62
        }
}
OBJECTIVES To characterize the homeostasis of CD4FoxP3 regulatory T cells (Treg) and its association with immune hyperactivation in the disease progression of chronic HIV-1 infection. DESIGN Treg proliferation and apoptosis markers were determined and the relation to disease progression and Treg activation was analyzed. METHODS Fifty-six HIV-1-infected highly active antiretroviral therapy (HAART)-naive subjects and 17 HAART-treated subjects were enrolled. Proliferation and apoptosis of Treg… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

CD4+FOXP3+ Regulatory T-Cell Subsets in Human Immunodeficiency Virus Infection

VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Differential upregulation of CD38 on different T-cell subsets may influence the ability to reconstitute CD4 q 2010 Lippincott Williams & Wilkins www.jaids.com

JM Benito, M Lopez, S Lozano
  • J Acquir Immune Defic Syndr Volume 54, Number
  • 2010
VIEW 1 EXCERPT

FOXP 3 expressing CD 127 lo CD 4 + T cells inversely correlate with CD 38 + CD 8 + T cell activation levels in primary HIV - 1 infection

LC Ndhlovu, CP Loo, G Spotts
  • J Leukoc Biol
  • 2008