Increased transcription of ubiquitin-proteasome system components: molecular responses associated with muscle atrophy.

@article{Price2003IncreasedTO,
  title={Increased transcription of ubiquitin-proteasome system components: molecular responses associated with muscle atrophy.},
  author={Stephen R. Price},
  journal={The international journal of biochemistry & cell biology},
  year={2003},
  volume={35 5},
  pages={617-28}
}
  • Stephen R. Price
  • Published 2003 in
    The international journal of biochemistry & cell…
Muscle atrophy is a common consequence of catabolic conditions like kidney failure, cancer, sepsis, and acute diabetes. Loss of muscle protein is due primarily to activation of the ubiquitin-proteasome proteolytic system. The proteolytic responses to catabolic signals include increased levels of mRNA that encode various components of the system. In the case… CONTINUE READING