Increased time exposure to tenofovir is associated with a greater decrease in estimated glomerular filtration rate in HIV patients with kidney function of less than 60 ml/min/1.73 m2.

@article{Fafin2012IncreasedTE,
  title={Increased time exposure to tenofovir is associated with a greater decrease in estimated glomerular filtration rate in HIV patients with kidney function of less than 60 ml/min/1.73 m2.},
  author={Coraline Fafin and Pascal Pugli{\`e}se and Jacques Durant and V{\'e}ronique Mondain and V{\'e}ronique Rahelinirina and Francine de Salvador and C Ceppi and Isabelle Perbost and Eric Rosenthal and Pierre Marie Roger and Eric Cua and Pierre Dellamonica and Vincent L M Esnault and C. Pradier and Olivier P Moranne},
  journal={Nephron. Clinical practice},
  year={2012},
  volume={120 4},
  pages={c205-14}
}
Tenofovir (TDF), atazanovir (ATAZ) and indinavir (IND) have been reported as possible risk factors for incident chronic kidney disease (CKD) in HIV-infected patients. We investigated the relationship between the duration of antiretroviral exposure and estimated glomerular filtration rate (eGFR) evolution in CKD patients. In a cohort of 1,750 HIV-infected patients, we identified 121 CKD patients with a mean follow-up of 44 ± 35 months. The relationship between mean eGFR at baseline, eGFR slope… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Reproduced with the permission

  • AG S.Karger, Basel
  • 2012

A comparison of cystatin Cand creatinine - based prediction equations for the estimation of glomerular filtration rate in black South Africans

  • R Scherzer, M Estrella, +4 authors MG Shlipak
  • Nephrol Dial Transplant
  • 2011

Compara - tive analysis of the new CKD epidemiology collaboration and the modification of diet in renal disease equations for estimation of glomerular filtration rate in HIV - 1 - infected subjects

  • A Gagneux-Brunon, C Mariat, P Delanaye
  • AIDS Res Hum Retroviruses
  • 2011

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