Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases.

Abstract

Reverse transcription coupled with DNA amplification has become a well-established and powerful molecular technique for studying ribonucleic acids. However, the efficiency of those reactions is largely dependent on the molecular properties of currently used reverse transcriptases (RTs). Engineered and natural RT variants with improved thermostability and… (More)
DOI: 10.1016/j.jmb.2009.07.081

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@article{Alvarez2009IncreasedTA, title={Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases.}, author={Mar Alvarez and Tania Matamoros and Luis Men{\'e}ndez-Arias}, journal={Journal of molecular biology}, year={2009}, volume={392 4}, pages={872-84} }