Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

@article{Qin2008IncreasedSA,
  title={Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment},
  author={Liya Qin and Jun He and Richard N. Hanes and Olivera Pluzarev and Jau-Shyong Hong and Fulton T Crews},
  journal={Journal of Neuroinflammation},
  year={2008},
  volume={5},
  pages={10 - 10}
}
Cytokines and alcohol share a common modulation of inflammation and hormones as well as being implicated in multiple diseases, but the mechanisms are poorly understood. The purpose of this study was to investigate the interaction of liver, serum and brain cytokines as well as whether ethanol would potentiate endotoxin (Lipopolysaccharide, LPS) responses once ethanol had cleared. Male C57BL/6J mice were treated intragastrically with water (control) or ethanol (5 g/kg, i.g., 25% ethanol, w/v… CONTINUE READING
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