Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities.

@article{Licht2010IncreasedSA,
  title={Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities.},
  author={Carmilla M. M. Licht and Sophie A. Vreeburg and Arianne K B van Reedt Dortland and Erik J Giltay and Witte J. G. Hoogendijk and Roel H Derijk and Nicole Vogelzangs and Frans G Zitman and Eco J. C. de Geus and Brenda W. J. H. Penninx},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 5},
  pages={2458-66}
}
CONTEXT Stress is suggested to lead to metabolic dysregulations as clustered in the metabolic syndrome, but the underlying biological mechanisms are not yet well understood. OBJECTIVE We examined the relationship between two main str systems, the autonomic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis, with the metabolic syndrome and its components. DESIGN The design was baseline data (yr 2004-2007) of a prospective cohort: the Netherlands Study of Depression and Anxiety… CONTINUE READING