Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerol-induced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension.

@article{Liu2007IncreasedSA,
  title={Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerol-induced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension.},
  author={Dao Liu and Florian Nikolaus Thilo and Alexandra Scholze and Antje Wittstock and Zhi Gang Zhao and Christian Harteneck and Walter Zidek and Zhi Ming Zhu and Martin Tepel},
  journal={Journal of hypertension},
  year={2007},
  volume={25 4},
  pages={
          799-808
        }
}
OBJECTIVE Activation of nonselective cation channels of the transient receptor potential canonical (TRPC) family has been associated with hypertension. Whether store-operated channels, which are activated after depletion of intracellular stores, or second-messenger-operated channels, which are activated by 1-oleoyl-2-acetyl-sn-glycerol, are affected in essential hypertension is presently unknown. METHODS Using a polymerase chain reaction, an in-cell western assay and the fluorescent dye… CONTINUE READING
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