Increased sperm production in adult rats after transient neonatal hypothyroidism.

@article{Cooke1991IncreasedSP,
  title={Increased sperm production in adult rats after transient neonatal hypothyroidism.},
  author={Paul S. Cooke and Rex A Hess and Joseph P Porcelli and Esmail Meisami},
  journal={Endocrinology},
  year={1991},
  volume={129 1},
  pages={
          244-8
        }
}
In the preceding paper it was shown that transient neonatal hypothyroidism induced by treatment of rats from birth to day 25 with the goitrogen 6-propyl-2-thiouracil (PTU) is associated with increases in testis wt and DNA content of up to 80% during adulthood. The testis changes were accompanied by similar, though less marked, increases in the wt and DNA content of epididymis and accessory organs. The purpose of this study was to assess sperm production in these enlarged testes and measure… CONTINUE READING
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