Increased somatostatin and enkephalin-like immunoreactivity in the rat hippocampus following hippocampal kindling

@article{Wanscher1990IncreasedSA,
  title={Increased somatostatin and enkephalin-like immunoreactivity in the rat hippocampus following hippocampal kindling},
  author={Benedikte Wanscher and J\orn Kragh and DavidI. Barry and Tom Gert Bolwig and Jens Zimmer},
  journal={Neuroscience Letters},
  year={1990},
  volume={118},
  pages={33-36}
}
As neuropeptides may play a role in the electrical kindling model of epileptogenesis, hippocampal somatostatin, Met-enkephalin and cholecystokinin were studied by immunocytochemistry in rats 24 h following full hippocampal kindling (three stage 5 seizures). As control animals we used sham-kindled rats, unoperated rats and rats subjected to a single electroshock-induced seizure. In addition, the distribution of septohippocampal, cholinergic fibers and hippocampal mossy fibers were studied by… CONTINUE READING

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