Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study.

@article{Kathiresan2006IncreasedSL,
  title={Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study.},
  author={Sekar Kathiresan and James D. Otvos and Lisa Sullivan and Michelle J. Keyes and Ernst J. Schaefer and Peter W. F. Wilson and Ralph B. D'Agostino and Ramachandran S. Vasan and Sander J. Robins},
  journal={Circulation},
  year={2006},
  volume={113 1},
  pages={20-9}
}
BACKGROUND Levels of LDL cholesterol (LDL-C) are frequently not elevated in individuals with the metabolic syndrome (MetSyn). However, the atherogenic potential of LDL may depend on the number and size of LDL particles in addition to the cholesterol content of LDL. METHODS AND RESULTS We examined the sex-specific cross-sectional relations of small LDL particle number (determined by nuclear magnetic resonance spectroscopy) to the presence of MetSyn and its components in 2993 Framingham Heart… CONTINUE READING