Increased size of myocardial infarction in dogs with chronic hypertension and left ventricular hypertrophy.

@article{Koyanagi1982IncreasedSO,
  title={Increased size of myocardial infarction in dogs with chronic hypertension and left ventricular hypertrophy.},
  author={Samon Koyanagi and Charles L. Eastham and David G Harrison and M. D. Lanc{\'e} Marcus},
  journal={Circulation research},
  year={1982},
  volume={50 1},
  pages={
          55-62
        }
}
Impaired coronary reserve in animals and patients with left ventricular hypertrophy (LVH) might be expected to augment infarct size following coronary occlusion (CO). To test this hypothesis, the circumflex coronary artery was acutely occluded in 30 control dogs and in 28 renal hypertensive (HT)-LVH dogs during the conscious state. Hemodynamics and regional myocardial flow (microspheres) were measured. After 48 hours of CO, we assessed infarct size pathologically and area at risk by postmortem… CONTINUE READING

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