Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice.

@article{Bird2000IncreasedSO,
  title={Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice.},
  author={J. E. Bird and Mary R Giancarli and Toru Kurihara and Mark C. Kowala and Megan T Valentine and P H Gitlitz and Dipti Pandya and Michael H French and Stephen K. Durham},
  journal={Kidney international},
  year={2000},
  volume={57 1},
  pages={
          129-36
        }
}
UNLABELLED Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice. BACKGROUND The C-C chemokine receptor 2 (CCR2) is expressed on monocytes and facilitates monocyte migration. CCR2 is a prominent receptor for monocyte chemoattractant protein-1 (MCP-1). This chemokine recruits monocytes to sites of inflammation. It has been suggested that CCR2 and its ligand, MCP-1, play a role in the pathogenesis of glomerulonephritis. The goal of this study was to determine the… CONTINUE READING
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