Increased serum levels of ICAM-1, ELAM-1 and TNF-α in inflammatory disorders of the peripheral nervous system

@article{Musso2006IncreasedSL,
  title={Increased serum levels of ICAM-1, ELAM-1 and TNF-α in inflammatory disorders of the peripheral nervous system},
  author={Alessandro Musso and Gianluigi Zanusso and Matteo Bonazzi and Gianpaolo Tomelleri and B Bonetti and Giuseppe Moretto and M. Vio and Dr. S. Monaco},
  journal={The Italian Journal of Neurological Sciences},
  year={2006},
  volume={15},
  pages={267-271}
}
Endothelial intercellular adhesion molecule-1 (ICAM-1) and glycoprotein E-selectin (ELAM-1) allow the homing of leukocytes to inflammation sites. A circulating form of ICAM-1 markedly increases in inflammatory CNS disorders. In the present study, the serum levels of ICAM-1, ELAM-1 and tumor necrosis factor-α (TNF-α) were measured in patients with acute (AIDP) and chronic (CIDP) inflammatory demyelinating polyneuropathies and cryoglobulinemic neuropathy (CGN). Immunoenzymometric assays revealed… CONTINUE READING