Increased serum granulocyte colony-stimulating factor correlates with coronary artery dilatation in Kawasaki disease

@article{Samada2002IncreasedSG,
  title={Increased serum granulocyte colony-stimulating factor correlates with coronary artery dilatation in Kawasaki disease},
  author={Kazunori Samada and Hiroshi Igarashi and Hirohiko Shiraishi and Kiyohiko Hatake and Mariko Y. Momoi},
  journal={European Journal of Pediatrics},
  year={2002},
  volume={161},
  pages={538-541}
}
In acute-phase Kawasaki disease, neutrophils cause injury to the coronary arterial endothelium through the production of elastase. Previous research has demonstrated the modulation of neutrophil function and kinetics, such as development and maturation, by granulocyte colony-stimulating factor (G-CSF). To examine the correlation between G-CSF and cardiac complications in Kawasaki disease, functional activity of serum G-CSF and cytokines was measured by enzyme-linked immunosorbent assay in 30… CONTINUE READING