Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients

@article{Goodall2008IncreasedSF,
  title={Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients},
  author={Emily F. Goodall and Md. Shahidul Haque and Prof. K. E. Morrison},
  journal={Journal of Neurology},
  year={2008},
  volume={255},
  pages={1652-1656}
}
Iron misregulation promotes oxidative stress, a proposed pathological mechanism in neurodegenerative disease. The aim of this study was to evaluate serum iron metabolism indicators in 60 amyotrophic lateral sclerosis (ALS) patients and 44 age matched controls. Serum ferritin levels were significantly increased in ALS patients compared to controls (p < 0.001), while no differences in the levels of serum iron, transferrin, iron saturation or total iron binding capacity were found. Likewise no… CONTINUE READING